High Flow Oxygen Therapy

Key Details

High Flow therapy delivers humidified oxygen and air to baby at higher flows than traditional oxygen therapy.

The use of High Flow therapy as a non-invasive support therapy continues to grow in neonatal care. High Flow therapy delivers humidified oxygen and air to baby at higher flows than traditional oxygen therapy (1) and is increasingly used to help prevent escalation of respiratory care for infants (2).

High Flow provides several physiological benefits to optimise an infant’s respiratory effort.  These include reduction of dead space through nasopharyngeal wash out, reduction of inspiratory resistance and provision of variable distending pressure to help splint open airways (3,4). The delivery of the therapy via a heated, humidified system ensures increased lung compliance (5,6) and the use of a nasal cannula provides increased comfort to babies compared to other non-invasive therapies (7).

The Neoflow range works to streamline delivery of care, save users time, and reduce waste through dedicated therapy packs and easy therapy transitions between Invasive Ventilation, nCPAP and High Flow. Our High Flow products, protected by Biocote, aim to provide neonatal staff with a solution to help them deliver the best outcome for baby.

Featured Products

NeoFlow Nasal Cannula

For increased comfort our ultra-soft nasal cannula, with adjustable fixation pads, are made from hypoallergenic 3M™ Gentle Si and include a positioning tab for ease of positioning.

Read more about our NeoFlow nasal cannulas.

AquaVENT® NEO High Flow Circuitry

For ease of transition our NeoFlow High Flow circuits, with AquaVENT® NEO heated wire technology, are designed to allow the breathing systems to transition with the patient through their NICU journey.

Read more about our NeoFlow High Flow circuits.

BioCote® Antimicrobial Silver Technology

Our neonatal breathing systems are supplied with BioCote®, an antimicrobial silver additive to limit the numbers of microbes on the surface of the breathing circuit, protecting it from microbial colonisation.


1. Dani, Carlo, et al. “High flow nasal cannula therapy as respiratory support in the preterm infant.” Pediatric pulmonology 44.7 (2009): 629-634.
2. Wilkinson, Dominic, et al. “High flow nasal cannula for respiratory support in preterm infants.” Cochrane Database of Systematic Reviews 2 (2016).
3. El-Farghali, Ola G. “High-flow nasal cannula in neonates.” (2017): 641-642.
4. Lee Jr, Michael, and Joshua Nagler. “High-flow nasal cannula therapy beyond the perinatal period.” Current opinion in pediatrics 29.3 (2017): 291-296.
5. Ten Brink, Fia, Trevor Duke, and Janine Evans. “High-flow nasal prong oxygen therapy or nasopharyngeal continuous positive airway pressure for children with moderate-to-severe respiratory distress?.” Pediatric Critical Care Medicine 14.7 (2013): e326-e331.
6. Al-Alaiyan, S., M. Dawoud, and F. Al-Hazzani. “Positive distending pressure produced by heated, humidified high flow nasal cannula as compared to nasal continuous positive airway pressure in premature infants.” Journal of neonatal-perinatal medicine 7.2 (2014): 119-124.
7. Collins, C. L., et al. “A comparison of nasal trauma in preterm infants extubated to either heated humidified high-flow nasal cannulae or nasal continuous positive airway pressure.” European journal of pediatrics 173.2 (2014): 181-186.

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